Optimal intensity of oral anticoagulant therapy after myocardial infarction

Optimal intensity of oral anticoagulant therapy after myocardial infarction.

OBJECTIVES This study attempted to determine the optimal intensity of anticoagulant therapy in patients after myocardial infarction. BACKGROUND Treatment with oral anticoagulant therapy entails a delicate balance between over- (risk of bleeding) and under-anticoagulation (risk of thromboemboli). The optimal intensity required to prevent the occurrence of either event (bleeding or thromboembol...

Long-term anticoagulant therapy after myocardial infarction in women.

A multicentre trial from five medical departments in Oslo has been carried out to determine the value in women patients of one year's long-term anticoagulant therapy. Follow-up long-term laboratory control and anticoagulant dosage were performed at one centre (the Rikshospitalet). One hundred and fifty-nine patients were assigned randomly into two similar well-matched groups (control and treatm...

Long-term anticoagulant therapy after acute myocardial infarction.

A method to determine the optimal intensity of oral anticoagulant therapy.

Oral anticoagulant therapy has been shown to be effective for several indications. The optimal intensity of anticoagulation for each indication, however, is largely unknown. To determine this optimal intensity, randomised clinical trials are conducted in which two target levels of anticoagulation are compared. This approach is inefficient, since the choice of the target levels will be arbitrary...

Spontaneous intramural gastric haematoma as a complication of oral anticoagulant therapy mimicking acute myocardial infarction.

Delcourt A, Godeau P, Piette JC. Endomyocardial fibrosis in Behcet’s disease. Ann Rheum Dis 1997;56:205–208. 90. Albayram MS, Wityk R, Yousem DM, Zinreich SJ. The cerebral angiographic findings in Cogan syndrome. Am J Neuroradiol 2001;22:751–754. 91. Lunardi C, Bason C, Leandri M, Navone R, Lestani M, Millo E, Benatti U, Cilli M, Beri R, Corrocher R, Puccetti A. Autoantibodies to inner ear and ...